“Limitless Possibilities” – A New Law of Physics Could Predict Gene Mutations

Genetic sequencing concept

The researchers suppose they will exploit this new bodily regulation and discover the likelihood of mutations earlier than they happen.

A analysis crew from the College of Portsmouth has discovered a possible option to predict genetic mutations earlier than they happen.

In accordance with a research from the College of Portsmouth, a brand new bodily regulation may allow the early prediction of genetic mutations.

The research finds that the second regulation of knowledge dynamics, or “infodynamics,” behaves in another way than the second regulation of thermodynamics. This discovering may have main implications for a way genomics analysis, evolutionary biology, computing, huge knowledge, physics and cosmology will develop sooner or later.

The lead writer, Dr. Melvin Vopson, is from the College’s College of Arithmetic and Physics. He states, “In physics, there are legal guidelines that govern all the pieces that occurs within the universe, equivalent to how objects transfer, how power flows, and so on. Every thing relies on the legal guidelines of physics. Probably the most highly effective legal guidelines is the second regulation of thermodynamics, which states that entropy – a measure of dysfunction in an remoted system – can solely improve or keep the identical, however it can by no means lower.

That is an undisputed regulation referring to the arrow of time, which demonstrates that point solely strikes in a single route. It could actually solely circulate in a single route and can’t return.

He explains: “Think about two clear glass containers. Within the left facet you’ve got crimson gasoline molecules, which you’ll see, like crimson smoke. In the correct facet you’ve got blue smoke, and between them is a barrier. For those who take away the barrier, the 2 gases will start to combine and the colour will change. There isn’t a course of that this technique can bear to separate blue and crimson once more. In different phrases, you can not scale back entropy or prepare the system because it was earlier than with out expending power, as a result of entropy simply stays fixed or will increase over time.

Dr. Vopson is an data physicist. His analysis focuses on data programs, which may vary from the onerous drive of a laptop computer laptop to

DNA, or deoxyribonucleic acid, is a molecule made up of two lengthy strands of nucleotides that wrap round one another to type a double helix. It’s the hereditary materials in people and nearly all different organisms that carries genetic directions for improvement, functioning, development and replica. Nearly all cells in an individual’s physique have the identical DNA. Most DNA is discovered within the cell nucleus (the place it’s referred to as nuclear DNA), however a small quantity of DNA will also be discovered within the mitochondria (the place it’s referred to as mitochondrial DNA or mtDNA).

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Dr. Vopson and colleagues analyzed Covid-19 (Sars-CoV-2) genomes and discovered that their information entropy reduced with time: “The best example of something that undergoes a number of mutations in a short space of time is a virus. The pandemic has given us the ideal test sample as Sars-CoV-2 mutated into so many variants and the data available is unbelievable.”

He continues, “The Covid data confirms the second law of infodynamics and the research opens up unlimited possibilities. Imagine looking at a particular genome and judging whether a mutation is beneficial before it happens. This could be game-changing technology which could be used in genetic therapies, the pharmaceutical industry, evolutionary biology, and pandemic research.”

Reference: “Second law of information dynamics” by Melvin M. Vopson and S. Lepadatu, 11 July 2022, AIP Advances.
DOI: 10.1063/5.0100358

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